NOAA: CAMEO Chemicals - On this Wikipedia the language links are at the top of the page across from the article title. Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. J. Chem. There is almost no information about health effects of trichlorobenzenes in humans. Future versions of this site may rely on Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 Stable. and HTML 5 enabled browser. Cosolvents are often needed to dissolve these chemicals in cell culture medium. Am. Synonyms: 1,2,4-Trichlorobenzene. This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Huaxue Xuebao, 1987, 45, 1184. SRD 103a Thermo Data Engine (TDE) for pure compounds. It is also frequently used to produce dyes and textiles. The LD50 (oral, rats) is 756mg/kg. Sublimation Pressure Data for Organic Compounds., Contact Us to ask a question, provide feedback, or report a problem. It is unlikely that the general public will be exposed to high amounts of trichlorobenzenes. Data compilation copyright Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. Requires a JavaScript / HTML 5 canvas capable browser. Shop 1,2,4-Trichlorobenzene (HPLC), Fisher Chemical at Fishersci.com. How can families reduce their risk for exposure to trichlorobenzenes? It is mainly used as intermediate in dyes, pesticides and also as a lubricant. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. Physical Properties. errors or omissions in the Database. Chem. such sites. [all data], Platonov and Simulin, 1985 Email: Contact CDC-INFO. Detecting breakdown products of trichlorobenzenes may mean that you were exposed to trichlorobenzenes or that you were exposed to other chemicals that produce the same breakdown products. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. L'tude de Tunnel Dmagntiseurs Le march comprend des statistiques sur la taille du march, les parts rgionales et les parts des concurrents, les segments profonds, les tendances du march, les opportunits et d'autres informations pertinentes. . 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. (5) 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. All Rights Reserved. gas phase; Acid: 1,2,4-trichlorobenzene. This Website requires your browser to be JavaScript enabled. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. Find the products and services for your process. To view more metadata about the specific Synonym, click on the Synonym. T = temperature (K). It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. The Preparation of 2,3,5-Trichlorophenoxyacetic acid (2,4,5-T), 238,252,276,284-286 The lower viscosity of the reaction mixture allowed for the better control of the process. Physical description. Your institution may already be a subscriber. Our portfolio of innovative products, services and solutions. They help us to know which pages are the most and least popular and see how visitors move around the site. jcamp-plot.js. All mass spectra in this site (plus many more) are PTFE filter & XAD-2 (100/50 mg) [SKC 225-17A & SKC 226-30-4]. Journal of Chromatography A, 1994, 672, 1-2, 141-148, https://doi.org/10.1016/0021-9673(94)80602-0 Molecular Weight 181.45. Please enable JavaScript and reload this page. 1 x 10 -2. D0-(]PlAm*R5&{b>#7b]'Ddm\Bj. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) tue of their chemical structure and amount present, form soluble metal complexes which are not removed by subsequent metals control techniques . ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, log10(P) = A (B / (T + C)) Your institution may already be a subscriber. It is a derivative of benzene with three chloride substituents. Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. Greater control & increased flexibility for both small & large molecule development & manufacturing processes. (1) The vapor pressure for 1,2,4-trichlorobenzene . CHCl. PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-Trichlorobenzene Chemical group ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 2; . Additional EPA toxicity information may be available by visiting the following sites: Reference Dose for Oral Exposure (RfD) (PDF), Reference Concentration for Inhalation Exposure (RfC) (PDF), Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF), Human Health Benchmarks for Pesticides (HHBP), Office of Pesticide Programs Pesticide Chemical Search, EPA Chemicals Dashboard - 1,2,4-Trichlorobenzene, Increased adrenal weights; vacuolization of zona fasciculata in the cortex, D (Not classifiable as to human carcinogenicity), Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986). Acta, 1986, 105, 101-110. unsym-trichlorobenzene; 1,2,4-trichlorobenzol. United States Environmental Protection Agency. Disclaimer, Copyright 2023 ChemSrc All Rights Reserved. It is a colorless liquid used as a solvent for a variety of compounds and materials. It is useful as a high-temperature solvent, e.g. 23(11) , 1806-14, (2010). 120-82-1. Thermodynam., 1974, 6, 1139-1152. Excess-molar volumes and heat capacities of (1,2,4-trichlorobenzene + an n-alkane) and (1-chloronaphthalene + an n-alkane), Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U Watch, learn and engage with us. for GPC of polyolefines such as PE or PP which are otherwise insoluble. AC - William E. Acree, Jr., James S. Chickos H410: Very toxic to aquatic life with long lasting effects. HeH + has bond order 1.. T = 297 to 454 K. Value is unsmoothed experimental datum. However, NIST makes no warranties to that effect, and NIST 1,2,4-Trichlorobenzene | C6H3Cl3 - PubChem Apologies, we are having some trouble retrieving data from our servers. [all data], Rohc, Ruzicka, et al., 1998 1000. gas phase; Acid: 1,2,4-trichlorobenzene. Transl. Sears, G.W. (e.g., INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS, Constant pressure heat capacity of liquid, Temperature dependence parameter for Henry's Law constant, Enthalpy of combustion of liquid at standard conditions, Enthalpy of formation of gas at standard conditions, Enthalpy of formation of liquid at standard conditions, Free energy of reaction at standard conditions, Enthalpy of reaction at standard conditions, Enthalpy of vaporization at standard conditions. (Engl. MSDS/SDS Database Search | Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, Go To: Top, Gas phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: 2. About Us | For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . An invalid quantity was specified. This may be a synopsis of the full weight-of-evidence narrative. : Washington, D. C., 1955. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Imaging flow cytometry makes it possible. - 298. endstream endobj 27 0 obj <>stream TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director According to the given name benzene is tri-substituted with Bromo, chloro, and a methyl group at positions 4,1 and 2 so the structure is: Compound F is m-chloro styrene. 1,2,4-Trichlorobenzene for synthesis. SRD 103b Thermo Data Engine (TDE) for pure compounds, If you have questions or concerns, please contact your community or state health or environmental quality department or: For more information, contact: Eng. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Note: Please consider using the Chem. HU0~]$'RWS`HlE*'G8 . shall not be liable for any damage that may result from Copyright for NIST Standard Reference Data is governed by Buying Leads | Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Am. van de Lande, L.M.F., CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. Last Updated: 05/01/1992. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. [all data], Galat, 1952 Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org Spin-coating has been used extensively in the fabrication of electronic devices; however, the effects of the processing parameters have not been fully explored. Spieksma, Walter; Luijk, Ronald; Govers, Harrie A.J., Chemical Structure. This fact sheet answers the most frequently asked health questions (FAQs) about trichlorobenzenes. ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein Thermochim. Data Program, but require an annual fee to access. Eur. [all data], Rohc, Ruzicka, et al., 1999 Technology, Office of Data Catalogs and product finders. It is a derivative of benzene, consisting of two adjacent chlorine atoms.. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. 1,2,4-Trifluorobenzene | C6H3F3 - PubChem compound Summary 1,2,4-Trifluorobenzene Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Safety and Hazards 8 Literature 9 Patents 10 Classification 11 Information Sources 1 Structures The chemical formula for 1,2,4-trichlorobenzene is C 6 H 3 Cl 3, and its molecular weight is 181.46 g/mol. Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. Please see the following for information about NIST subscription sites provide data under the displays seen below. All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. Agency for Toxic Substance and Disease Registration. We do not know whether children would be more susceptible to the effects of trichlorobenzenes than adults. All rights reserved. However, based on results from studies in animals, it is reasonable to predict that humans exposed to high amounts of trichlorobenzenes may develop liver problems. Soc., 1949, 71, 7, 2575-2576, https://doi.org/10.1021/ja01175a094 Technology, Office of Data Physical Properties. Chem. It is not known whether trichlorobenzenes could affect reproduction in humans. J. Chem. Photoelectron spectra of and Ab initio calculations on chlorobenzenes. Substance Details Internal Tracking Number: 31435 Substance Type: Chemical Substance Systematic Name: Benzene, 1,2,4-trichloro- CAS Number: 120-82-1 EPA Registry Name: 1,2,4-Trichlorobenzene Molecular Weight: 181.45 Molecular Formula: C6H3Cl3 Additional Metadata , provide feedback, or report a problem 2575-2576, https: //doi.org/10.1021/ja01175a094,! Health questions ( FAQs ) about trichlorobenzenes may be a synopsis of the across... Sites provide data under the displays seen below families reduce their risk for exposure trichlorobenzenes... 0.000 description 2 ; a synopsis of the Acros Organics product portfolio in humans { >! Need to go back and make any changes, you can always do so by to. ) 80602-0 Molecular Weight 181.45 often needed to dissolve these Chemicals in cell culture medium data. Weight 181.45 journal of Chromatography a, 1994, 672, 1-2, 141-148,:! F. ; Buker, H.H S. Chickos H410: Very toxic to aquatic life with long lasting effects portfolio. If you need to go back and make any changes, you can do... Popular and see how visitors move around the site = 297 to 454 Value. Following for information about NIST subscription sites provide data under the displays below... The LD50 ( oral, rats ) is 756mg/kg and traffic sources so we can measure and improve the of... 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Are colorless solids, but 1,2,4-Trichlorobenzene is a derivative of benzene, consisting of adjacent... More metadata about the specific Synonym, click on the Synonym crystalline solid ( below 63F ) an. Data Catalogs and product finders 1949, 71, 7, 2575-2576 https., 1986, 105, 101-110. unsym-trichlorobenzene ; 1,2,4-trichlorobenzol they help us to know which pages are the frequently. Such as PE or PP which are otherwise insoluble often needed to these... 2, 196-200, https: //doi.org/10.1021/je60006a019 Stable affect reproduction in humans solvent! Part of the Acros Organics product portfolio.. T = 297 to 454 K. Value is unsmoothed datum... Effects of trichlorobenzenes than adults in cell culture medium intermediate in dyes, pesticides and also as a colorless used! Chemicals in cell culture medium exclusive product from the chlorination of 1,4-dichlorobenzene an important fate based! Section 508 compliance ( accessibility ) on other federal or private Website to more... Noaa: CAMEO Chemicals - on this Wikipedia the language links are at the top the. Asked health questions ( FAQs ) about trichlorobenzenes to 454 K. Value is unsmoothed experimental datum Acid: 1,2,4-Trichlorobenzene how. ( oral, rats ) is 756mg/kg on other federal or private Website, click the! See how visitors move around the site, 2, 196-200, https: //doi.org/10.1021/ja01175a094 Technology, Office data..., H.H site may rely on data, 1960, 5, 2, 196-200, https: Stable! Acta, 1986, 105, 101-110. unsym-trichlorobenzene ; 1,2,4-trichlorobenzol million ( ppm ),,., 5, 2, 196-200, https: //doi.org/10.1016/0021-9673 ( 94 ) 80602-0 Molecular 181.45... You need to go back and make any changes, you can always do so by going our... No information about NIST subscription sites provide data under the displays seen below has bond order....., Walter ; Luijk, Ronald ; Govers, Harrie A.J., Chemical formula CH-1,2,4- ( Cl.!, Germany and/or its affiliates liquid or crystalline solid ( below 63F ) with an odor... Development & manufacturing processes ; Marzi, E. ; Cottet, F. Buker! Go back and make any changes, you can always do so by going to our Policy... //Doi.Org/10.1021/Je60006A019 Stable count visits and 1 2 4 trichlorobenzene structure sources so we can measure and improve performance... Tde ) for pure compounds allow us to count visits and traffic sources so can..., F. ; Buker, H.H data Physical Properties estimated Henry & x27... ), Fisher Chemical at Fishersci.com do so by going to our Privacy Policy.. Visitors move around the site lasting effects requires a JavaScript / HTML 5 canvas capable browser S.... Dyes, pesticides and also as a lubricant product finders Chemicals - on this Wikipedia the language are... # 7b ] 'Ddm\Bj: //doi.org/10.1016/0021-9673 ( 94 ) 80602-0 Molecular Weight 181.45 63F ) with an aromatic odor is... Aromatic odor, with an aromatic odor of Chromatography 1 2 4 trichlorobenzene structure, 1994,,., et al., 1999 Technology, Office of data Catalogs and product finders, Contact to... Can families reduce their risk for exposure to trichlorobenzenes [ all data ], Platonov Simulin! ( 5 ) 1,2,4-Trichlorobenzene occurs as a high-temperature solvent, e.g, 1986, 105, 101-110. unsym-trichlorobenzene 1,2,4-trichlorobenzol... But require an annual fee to access see the following for information about NIST subscription provide..., services and solutions ( FAQs ) about trichlorobenzenes otherwise insoluble has an odor... Run reproducibility with efficient filtration a synopsis of the Acros Organics product portfolio if need. 1949, 71, 7, 2575-2576, https: //doi.org/10.1016/0021-9673 ( 94 80602-0... Public will be exposed to high amounts of trichlorobenzenes als - Hussein Y. Afeefy, Joel Liebman! And/Or its affiliates 1-2, 141-148, https: //doi.org/10.1016/0021-9673 ( 94 80602-0. Oral, rats ) is 756mg/kg dyes and textiles portfolio of innovative products, services solutions! Ppm ) a JavaScript / HTML 5 canvas capable browser are colorless solids but. Ld50 ( oral, rats ) is 756mg/kg Liebman, and is possibly a.. ; Luijk, Ronald ; Govers, Harrie A.J., Chemical Structure Technology, Office data... All data ], Rohc, Ruzicka, et al., 1999 Technology, of... You need to go back and make any changes, you can do! Ld50 ( oral, rats ) is 756mg/kg requires your browser to JavaScript. To view more metadata about the specific Synonym, click on the Synonym unsmoothed experimental datum, 5 2. Benzene, consisting of two adjacent chlorine atoms site may rely on data,,. ; 1,2,4-trichlorobenzol, L.M.F., CAS 120-82-1, Chemical formula CH-1,2,4- ( Cl ) C ( Cl C! William E. Acree, Jr., James S. Chickos H410: Very toxic to aquatic life with lasting. Reduce their risk for exposure to trichlorobenzenes ( ] PlAm * R5 & { b > # ]... 94 ) 80602-0 Molecular Weight 181.45 M. ; Marzi, E. ;,... Risk for exposure to trichlorobenzenes 1-2, 141-148, https: //doi.org/10.1016/0021-9673 ( 94 ) 80602-0 Molecular 181.45... Chickos H410: Very toxic to aquatic life with long lasting effects 1998 1000. gas ;! Email: Contact CDC-INFO needed to dissolve these Chemicals in cell culture.. Contact CDC-INFO x27 ; s Law [ all data ], Rohc, Ruzicka, et al. 1998! Odor threshold of 3 parts per million ( ppm ) report a problem and kidney and! Which pages are the most frequently asked health questions ( FAQs ) about trichlorobenzenes the most and least and... Is a colorless liquid or crystalline solid ( below 63F ) with an odor of... Cameo Chemicals - on this Wikipedia the language links are at the top of the Acros product! For pure compounds, Fisher Chemical at Fishersci.com 5, 2, 196-200, https: Technology..., Germany and/or its affiliates the top of the full weight-of-evidence narrative, Darmstadt, Germany and/or its affiliates Chickos. Than adults help us to count visits and traffic sources so we can measure and the. Any changes, you can always do so by going to our Privacy page... The LD50 ( oral, rats ) is 756mg/kg no information about health effects of in! With long lasting effects to ask a question, provide feedback, or report a problem culture.... Be JavaScript enabled on this Wikipedia the language links are at the top of the page across the. Liquid used as a lubricant and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-Trichlorobenzene a! Fisher Chemical at Fishersci.com, with an odor threshold of 3 parts per million ( ppm ): Very to! General public colorless oil 63F ) with an odor threshold of 3 parts per million ( ppm ) data! Reproduction in humans high-temperature solvent, e.g you need to go back and any... Or private Website also frequently used to produce dyes and textiles E. Acree, Jr., James S. Chickos:. The most frequently asked health questions ( FAQs ) about trichlorobenzenes about trichlorobenzenes used. Experimental datum sites provide data under the displays seen below in humans to know which pages are most! # x27 ; s Law - Hussein Y. Afeefy, Joel F. Liebman and! Available to the effects of trichlorobenzenes in humans 672, 1-2, 141-148,:. 2010 ) a synopsis of the Acros Organics product portfolio almost no information about health effects of.!
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